IDSI Director Sanghyuk Shin and Co-Director Vladimir Minin are leading a five-year NIH R01-funded study to understand how TB spreads in populations affected by HIV. Advanced genetic techniques will be used to identify within-host Mycobacterium tuberculosis complex (Mtbc) heterogeneity among TB patients in Botswana. This data will then be integrated with epidemiological and spatial data to help us track how TB spreads. This project is expected to produce groundbreaking information for identifying TB transmission “hotspots”, which can guide public health interventions to prevent the transmission of this deadly global health threat.
Additional information can be found at the NIH Reporter.